B12 doses, benefits and side effects have been well studied in scientific studies and is overwhelmingly safe. Vitamin B12 foods are not very reliable sources of B12 so nutritional supplements, in their active methylated form, are recommend by Dr. Wald to many of his patients.
Methylcobalamin (mecobalamin, MeCbl, or MeB12) is a cobalamin, a form of vitamin B12. It differs from cyanocobalamin in that the cyano group at the cobalt is replaced with a methyl group. Methylcobalamin features an octahedral cobalt(III) centre and can be obtained as bright red crystals. From the perspective of coordination chemistry, methylcobalamin is notable as a rare example of a compound that contains metal–alkyl bonds. Nickel–methyl intermediates have been proposed for the final step of methanogenesis.
Methylcobalamin is equivalent physiologically to vitamin B12, and can be used to prevent or treat pathology arising from a lack of vitamin B12 intake (vitamin B12 deficiency).
Methylcobalamin that is ingested is not used directly as a cofactor, but is first converted by MMACHC into cob(II)alamin. Cob(II)alamin is then later converted into the other 2 forms, adenosylcobalamin and methylcobalamin for use as cofactors. That is, methylcobalamin is first dealkylated and then regenerated.
Nutrition in the form of diet and nutritional supplements are not an accepted treatment for COVID-19. Nutrition is supportive for overall health and nutrition status. The Center of Disease Control and the Food and Drug Administration do not consider nutritional therapies as a treatment for COVID-19. Your use of nutritional products and information on this website or at IntMedNY.com is for educational purposes only and is not to be considered as medical or health advice.
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